PME3211 Microsystem LabChips for BioMedical Applications (生醫微型系統晶片)

(Spring 2023)


Course Information

Instructor:     Liu, Cheng-Hsien
            Office: Room 517, Engineering Building #1
            Phone: (03) 5742496

Lectures:      Thursday 9:00am-12:00 (~150 minutes/week, one or two breaks in each-week class)
            Location:  Room 214, Engineering Building #1

Course Web site:



Course Objectives

The goal of this course is to provide students with basic concepts, principles, novel design of Microsystem LabChips for the applications of biomedicine/microfluidics/precise medicine as well as Lab chip microfabrication techniques. This course also aims at encouraging students to read state-of-the-art technology papers and present their thinking professionally to build up global views and capability.


General Info

§  Textbook:  My class notes. (eLearn downloadable files)

§  Recommended References:

§   Lab on Chip journal papers publication (

§  Sensors and Actuators B: Chemical Journal papers publication (some) ( )

§  Lectures are in Chinese mandarin, class notes are in English; students’ oral presentation in Chinese mandarin with all turn-in material required in English.

o   Grading:


Course  Topics: (tentative)


Lecture Schedule

Course Introduction

Feb. 16

Micro/Nano Fabrication & Soft Lithography Techniques (I)

Feb. 23

Micro/Nano Fabrication & Soft Lithography Techniques (II)

March 2

Digital MicroFluidics (Droplets)

March 9

(Continuous) MicroFluidic Systems

March 16

1st Class Presentation

March 23 & 30

Invited Topics (IC-based Biosensors -I)


April 13

Invited Topics (IC-based Biosensors -II)

Invited Topics (Lung Chips, Tumor Chips Inflammation Chips)

April 20


April 27

Fluidics Driven in Microsytem LabChips

May 4

Particles Driven in Microsytem LabChips

May 11

More Details and Applications

May 18

Final Presentation

May 25 & June 1

Final short report



Invited Lecturers:


Invited speaker


04/13 (9:00~9:50)


IC-based Biosensors (I)

04/20 (9:00~9:50)


IC-based Biosensors (II)

04/20 (10:10~12:00)


Lung Chips, Tumor Chips Inflammation Chips


Announcements: post on eLearn


Handouts: post on eLearn


Midterm Oral Presentation


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Last updated: Feb. 22, 2023 by Cheng-Hsien Liu