PME5232
Spanning Frontiers in Micro/Nano System Engineering and Molecular Diagnosis

(Spring 2004)

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Course Information

Instructors:

Liu, Cheng-Hsien           chhsliu@mx.nthu.edu.tw

 

Office:              Room 517, Engineering Building #1

 

Phone:              (03) 5715131 ext.3706

 

Office hours:     made by appt.

 

TA:

Chen-Ta Ho        d917725@oz.nthu.edu.tw

(PME5232)

Office:              Room 405, Engineering Building #1

 

Phone:              (03) 5715131 ext.3793

 

Ching-Chen Tu    d907709@oz.nthu.edu.tw

 

Office:              Room 405, Engineering Building #1

 

Phone:              (03) 5715131 ext.3793

 

Lectures:     Time        Wednesday 9:00am-12:00am
Location   Room 107, Engineering Building #1*

Course Web site for PME5232: http://mx.nthu.edu.tw/~chhsliu/NanoBio/PME5232_Liu.html　  

Course Web site for LSMM6456: http://www.life.nthu.edu.tw/~labchy/teaching/teaching.htm

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Course Objectives

The multi-disciplinary fields, bio-nanotechnology and Bio-Micro-ElectroMechanical Systems (BioMEMS) in miniature-system level, which combine the majors of life science, mechanical engineering, electrical engineering, material science and chemistry, are the stars of the biotechnology era.  The Goal of this course is to provide senior and graduate students with basic knowledge focusing on spanning frontiers in miniaturization system engineering, which uses integrated circuit fabrication or other nanofabrication technologies for their realization, and molecular diagnosis.  In this course, we seek to enhance these multi-disciplinary fields and emphasize the integration of life science and engineering in the miniaturization-scale technology via 1/3 of this course which focuses on students’ project presentation and discussion.

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General Info

    • Textbook:
      • Class notes.
    • Prerequisites:
      • Well, none.
    • Grading:
      • Written Exam (May 5th) :  40%
      • Final project report : 30%
      • Final project oral presentation : 30%
      • Extra 10% is reserved for your class discussion and performance

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Announcements

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Course Topics 

Lectures

Topics

1

Introduction and get-together meeting

2

Introduction to MEMS and nano technology

3

Basic principles in clinical diagnosis

4

Detection methods: Colorimetric, Fluorescence, Chemiluminescence, and Bioluminecence detection

5

Micro/Nano Fabrication technology (1)

6

Micro/Nano Fabrication technology (2)

7

Tools for systems biology-microarray, 2-D gel electrophoresis, etc.

8

Micro/Nano System Engineering for Bio-Applications (1)

9

Micro/Nano System Engineering for Bio-Applications (2)

10

Incorporation of MEMS in diagnosis

11

Examples of commercial products (Agilent's BioAnalyzer 2100)

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Handouts

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Final Projects

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Links to Other Sites

MEMS Clearinghouse

MEMS Interchange

Semiconductor Subway

Stanford MEMS Facility    

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Last updated: Feb. 2, 2004 by Cheng-Hsien Liu